William Ernest Castle

One of the earliest experimental geneticists; his 1901 paper was the first on Mendelism in America. Trained as an embryologist. Studies of inbreeding showed that interactions among "modifier" genes could create previously unseen variation. Pioneered use of Drosophila in genetics, but worked mostly on rodents. A eugenicist in the early 1920's before turning against the movement a few years later, along with most American geneticists.

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