Modeling of Signal Release by Attached Bacteria

2/26/02


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Table of Contents

Modeling of Signal Release by Attached Bacteria

Introduction ? Bacterial Factoids

Introduction ? Habitat

Quorum sensing

DRIVING QUESTION

Background

Cells as solute sources

Methods

Cell as a ‘perfect absorber’

Cartesian vs. spherical geometry

‘Diffusional Sphere’ = 10 rBact

Cells as source: Constant concentration at cell surface

Can a cell maintain a constant concentration at its surface?

Relevant boundary condition: Constant total flux from cell

Point source and sphere converge

Model: continuous point source Boundary condition: constant q, C(?) = 0

Elevated concentration inside the cell

What is the relationship with cell size?

Answer: SIZE DOES NOT MATTER

What if the ‘cell’ increases q [M T-1]?

C(r) linear with q

Diffusional Shell linear with q

Cell clusters

Attachment

Attachment - Uptake

Attachment - Uptake

Summary

Summary

Conclusions

Summary

Prediction/conjecture

Conclusions

Author: Jill Schmidt

Email: schmidt@nceas.ucsb.edu

Home Page: http://www.nceas.ucsb.edu/~schmidt/

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